Could a gentle brain ZAP ease severe depression in down syndrome?

NCT ID NCT06866925

First seen Jun 13, 2026 · Last updated Jun 17, 2026 · Updated 1 time

Summary

This study tests a non-drug treatment called transcranial direct current stimulation (tDCS) for depression with catatonia in adults with Down syndrome. 62 participants will receive either real or fake tDCS for 15 sessions. Researchers will measure changes in symptoms, safety, and brain activity to see if this gentle brain stimulation can help.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hopital Vinatier

    RECRUITING

    Lyon, Auvergne-Rhône-Alpes, 69678, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

catatonia Down syndrome major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.