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New study tracks how Gene-Targeted combo fights tough lung cancer in everyday practice

NCT ID NCT06494540

Recruiting now Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study follows 600 adults in Germany with a type of advanced lung cancer that has spread and carries certain high-risk gene mutations. Participants receive a standard triple-drug treatment (tremelimumab, durvalumab, and platinum chemo) as their first therapy. Researchers will track survival over two years to see how well the treatment works in real-world settings, especially for patients with specific genetic profiles.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Bad Homburg, Germany

  • Research Site

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    Berlin, Germany

  • Research Site

    WITHDRAWN

    Celle, Germany

  • Research Site

    RECRUITING

    Chemnitz, Germany

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    Frankfurt, Germany

  • Research Site

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    Georgsmarienhütte, Germany

  • Research Site

    WITHDRAWN

    Gera, Germany

  • Research Site

    RECRUITING

    Goslar, Germany

  • Research Site

    RECRUITING

    Halle-Dolau, Germany

  • Research Site

    RECRUITING

    Hanover, Germany

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    Herne, Germany

  • Research Site

    RECRUITING

    Koln-Mehrheim, Germany

  • Research Site

    RECRUITING

    Mainz, Germany

  • Research Site

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    Marburg, Germany

  • Research Site

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    Münnerstadt, Germany

  • Research Site

    RECRUITING

    Neuss, Germany

  • Research Site

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    Offenbach, Germany

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    Ravensburg, Germany

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    Rüsselsheim am Main, Germany

  • Research Site

    RECRUITING

    Treuenbrietzen, Germany

  • Research Site

    RECRUITING

    Ulm, Germany

  • Research Site

    RECRUITING

    Wiesbaden, Germany

  • Research Site

    RECRUITING

    Zwickau, Germany

Conditions

Explore the condition pages connected to this study.

NON-SQUAMOUS METASTATIC NON-SMALL-CELL LUNG CARCINOMA NON-SQUAMOUS METASTATIC NON-SMALL-CELL LUNG CARCINOMA