Can ancient chinese health practices ease depression?
NCT ID NCT05799586
First seen Sep 22, 2026 · Last updated Sep 23, 2026 · Updated 1 time
Summary
Researchers are testing a six-week Traditional Chinese Medicine health preservation course for Hong Kong Chinese adults with moderate depression. The course teaches lifestyle and self-care practices based on TCM principles. Participants attend six two-hour sessions and practice at home for six weeks. The study measures changes in depressive symptoms and anxiety to see if the approach is feasible and worth testing in a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a Traditional Chinese Medicine health preservation course combining lifestyle and self-care practices
- What this could lead to
- If it works, this could offer a low-cost, culturally familiar way to help people manage mild to moderate depression alongside standard care.
- What could go wrong
- This is a small pilot study of 31 people, so it may not show a clear benefit or may not generalise to other groups. Participants still receive usual care, and the course is not a replacement for standard treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Aug 2023
- Finished
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Jan 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Hong Kong Chinese adults aged 18-years-old to 65-years-old; * diagnosed with moderate level of depression (a score of 10\~20), evaluated by the Patient Health Questionnaire-9 (PHQ-9); * can communicate in spoken Cantonese and written Chinese; * willing to provide written informed consent and be able to adhere to the study protocol. Exclusion Criteria: * being pregnant or during the lactation, or plan to get pregnant; * new onset or change of antidepressant medication or dosage in the last 3 months; * PHQ-9 score≥20, meaning a severe level of depression; * with a previous or present diagnosis of psychotic disorders as screened by the Chinese version of the Structured Clinical Interview for DSM-IV; * the score of Hong Kong Montreal Cognitive Assessment less than 22; * significant suicidal risk as rated by the Hamilton Depression Rating Scale item on suicide (score ≥3); * with diagnosis of illness which can interfere the individuals to participate or adhere to the modified lifestyle; * with diagnosis of medical conditions, which are not suitable to modify diet or do physical activities recommended by physicians; * joining in another clinical trial during the study period; * with any major medical condition that causes depression based on the judgement of the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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School of Nursing, the Hong Kong Polytechnic University
Hong Kong, Hong Kong
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