Experimental cell therapy for cervical cancer stalls after just 5 patients
NCT ID NCT05357027
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tested a new treatment called TC-E202 for people with advanced cervical cancer that had stopped responding to standard treatments. TC-E202 uses a patient's own immune cells, which are genetically modified in a lab to better recognize and attack cancer cells. The trial was terminated early after enrolling only 5 participants, so we have very limited information about how safe or effective this approach might be.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TC-E202 cells (genetically engineered T cells targeting HPV16 E6)
- What this could lead to
- If successful, this approach could point toward a new treatment option for advanced cervical cancer that has not responded to standard therapies.
- What could go wrong
- This was a very early, small trial (only 5 participants) that was terminated early, so we have very little data on safety or effectiveness. The treatment also requires strong chemotherapy and IL-2, which can cause serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Xiaochun Cheng
Chongqing, Chongqing Municipality, 400000, China
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