Plant-Based cream shows promise for psoriasis in new trial

NCT ID NCT07426120

Recruiting now Disease control Sponsor: Psoriasis Research Institute of Guangzhou Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests a cream made from plant compounds (total coumarins) for treating psoriasis vulgaris. 300 adults will apply the cream or a placebo twice daily for 8 weeks. Researchers will check if the cream improves skin symptoms and quality of life, and monitor for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Total coumarin cream (TC Cream)
What this could lead to: If it works, this could provide a new, plant-based topical treatment option for people with mild-to-moderate psoriasis.
What could go wrong: This is a phase 3 trial, but the cream has already been approved in China. Still, results may differ in broader populations, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PHASE III PSORIASIS VULGARIS TOPICAL ADMINISTRATION

Contacts and locations

Locations

Department of Dermatology, SUNY Downstate Health Sciences University
RECRUITING

New York, New York, 11203, United States

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