New shot aims to keep TB at bay after treatment

NCT ID NCT03512249

Summary

This study tested whether a new vaccine called H56:IC31 could prevent tuberculosis (TB) from returning in people who had just been successfully treated for it. Over 800 HIV-negative adults in South Africa and Tanzania received either the vaccine or a placebo shot near the end of their standard TB treatment. The main goal was to see if the vaccine reduced the rate of TB disease coming back.

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Contacts and locations

Locations

  • NIMR Mbeya Medical Research Centre

    Mbeya, Tanzania

  • South African Tuberculosis Vaccine Initiative , Project Office, Brewelskloof Hospital , Harlem Street, Worcester

    Cape Town, Western Cape, 6850, South Africa

  • Task Clinical Research Centre

    Bellville, Cape Town, 7530, South Africa

  • The Aurum Institute

    Klerksdorp, North West, 2570, South Africa

  • The Aurum Institute: Tembisa Clinical Research Centre

    Tembisa, Gauteng, 1632, South Africa

  • University of Cape Town Lung Institute

    Mowbray, Cape Town, South Africa

Conditions

Explore the condition pages connected to this study.