Liver Function's impact on cancer drug tazemetostat under microscope
NCT ID NCT04241835
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times
Summary
This study looked at how the drug tazemetostat is processed in the body of people with advanced cancer who also have moderate or severe liver problems. It compared their blood drug levels to those with normal liver function. The goal was to understand safety and dosing, but the study was stopped early.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Antwerp University Hospital
Edegem, Antwerp, 2650, Belgium
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Centre Oscar Lambret
Lille, 59020, France
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Comprehensive Cancer Center of Nevada
Las Vegas, Nevada, 89014, United States
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Florida Cancer Specialists & Research Institute
Lake Mary, Florida, 32746, United States
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Gabrail Cancer Center
Canton, Ohio, 44718, United States
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Hematology Oncology Consultants
Royal Oak, Michigan, 48073, United States
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Institut Bergonie
Bordeaux, 33076, France
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Institut de Cancérologie Strasbourg Europe
Strasbourg, France
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Mary Crowley Cancer Research
Dallas, Texas, 75230, United States
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MedPolonia
Poznan, Greater Poland Voivodeship, 60693, Poland
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Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Chicago, Illinois, 60611, United States
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Rutgers Cancer Institute
New Brunswick, New Jersey, 08901, United States
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Summit Clinical Research, s.r.o
Bratislava, 831 01, Slovakia
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Virginia Cancer Specialists
Fairfax, Virginia, 22031, United States
Conditions
Explore the condition pages connected to this study.