New combo aims to shrink lymphoma tumors with less chemo

NCT ID NCT05551936

First seen Feb 18, 2026 · Last updated May 24, 2026 · Updated 12 times

Summary

This study tests a new combination of drugs for people with a type of slow-growing blood cancer called follicular lymphoma that has a high tumor burden. The treatment includes tazemetostat (a targeted pill) plus rituximab (an antibody) and a shortened course of bendamustine (chemotherapy). The goal is to see if this approach is safe and effective at making tumors disappear, while using less chemotherapy than standard care. About 42 adults will take part.

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Contacts and locations

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • University of Illinois Cancer Center

    Chicago, Illinois, 60612, United States

  • University of Wisconsin Carbone Cancer Center

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.