Could a tiny ear device ease Long-Term lyme symptoms?
NCT ID NCT05776251
First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 35 times
Summary
This study tests a small, non-invasive device that stimulates a nerve in the ear to see if it can help people with symptoms that persist after Lyme disease treatment. The trial will enroll 24 adults and focus on whether the device is safe, tolerable, and practical to use. It is one of the first to explore a non-antibiotic approach for post-treatment Lyme symptoms.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Lyme and Tick-Borne Diseases Research Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcutaneous auricular vagus nerve stimulation (taVNS) device
What this could lead to
If this works, it could point toward a non-drug way to ease lingering symptoms after Lyme disease treatment.
What could go wrong
This is a very small, early feasibility study with only 24 people. It is designed to test safety and tolerability, not effectiveness, so it may not lead to a proven treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.