New PET scan could spot Alzheimer's before autopsy

NCT ID NCT05641688

First seen Jan 07, 2026 · Last updated May 08, 2026 · Updated 21 times

Summary

This study tests a new PET scan tracer, [18F]PI-2620, to see if it can accurately detect tau protein buildup in the brains of people with Alzheimer's disease. About 200 adults aged 50 and older with a life expectancy of one year or less will receive the scan during life, and results will be compared to brain tissue analysis after death. The goal is to improve diagnosis of Alzheimer's without needing an autopsy.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alzheimer's Disease Center

    RECRUITING

    Braintree, Massachusetts, 02184, United States

  • American Carolina Clinical Research LLC

    TERMINATED

    Charlotte, North Carolina, 28273, United States

  • Banner Sun Health Research Institute

    RECRUITING

    Sun City, Arizona, 85352, United States

  • Barrow Neurological Institute

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • Baylor Research Institute

    RECRUITING

    Dallas, Texas, 75231, United States

  • Be Well Clinical Studies

    WITHDRAWN

    Lincoln, Nebraska, 68616, United States

  • Be Well Clinical Studies

    RECRUITING

    Round Rock, Texas, 78681, United States

  • Charter Research

    RECRUITING

    Winter Park, Florida, 32792, United States

  • ClinCloud Research

    RECRUITING

    Melbourne, Florida, 32940, United States

  • Darthmouth-Hitchcock Medical Center

    RECRUITING

    Lebanon, New Hampshire, 07366, United States

  • Esperanza Clinical

    RECRUITING

    Murrieta, California, 92562, United States

  • Galiz Research

    RECRUITING

    Hialeah, Florida, 33016, United States

  • Headlands Research

    WITHDRAWN

    Plymouth, Massachusetts, 02360, United States

  • Ichor Research

    RECRUITING

    Syracuse, New York, 13219, United States

  • Insight Clinical Trials LLC

    RECRUITING

    Beachwood, Ohio, 44131, United States

  • K2 Medical Research

    RECRUITING

    Lady Lake, Florida, 32159, United States

  • K2 Medical Research

    RECRUITING

    Maitland, Florida, 32751, United States

  • Miami Jewish Health Systems

    RECRUITING

    Miami, Florida, 33137, United States

  • Sante Clinical Research

    RECRUITING

    Kerrville, Texas, 78028, United States

  • Sutter Health

    RECRUITING

    San Francisco, California, 94114, United States

  • The Roskamp Institute

    TERMINATED

    Sarasota, Florida, 34243, United States

  • UC Los Angeles

    RECRUITING

    Los Angeles, California, 90095 - 7370, United States

  • UF College of Medicine - Jacksonville

    WITHDRAWN

    Jacksonville, Florida, 32209, United States

  • Valley Medical Research

    RECRUITING

    Centerville, Ohio, 45459, United States

  • Velocity Clinical Research

    RECRUITING

    East Syracuse, New York, 13057, United States

Conditions

Explore the condition pages connected to this study.