New combo therapy targets liver metastases in hard-to-treat cancers

NCT ID NCT04701476

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a two-part treatment for people with colorectal or non-small cell lung cancer that has spread to the liver and hasn't responded to standard therapies. The treatment combines a liver-directed procedure (TATE) that delivers a chemotherapy-like drug directly to the tumor with pembrolizumab, an immunotherapy that helps the immune system fight cancer. The goal is to see if this combination can shrink tumors and help people live longer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • China Medical University Hsinchu Hospital

    RECRUITING

    Hsinchu, Taiwan

  • Chung Shan Medical University Hospital

    RECRUITING

    Taichung, Taiwan

  • University of California, Irvine Medical Center

    RECRUITING

    Orange, California, 92868, United States

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