New combo tackles resistant gut tumors in early trial
NCT ID NCT05245968
First seen Jan 28, 2026 · Last updated May 06, 2026 · Updated 17 times
Summary
This early-phase study tests a new drug (TAS-116) combined with imatinib in people with advanced gastrointestinal stromal tumors (GIST) that no longer respond to imatinib alone. About 78 participants will receive different treatments to find the safest dose and see if the combo can shrink tumors or slow their growth. The study also compares the combo to TAS-116 alone or sunitinib alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Alfred Health
Melbourne, Australia
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Beijing Cancer Hospital
Beijing, China
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Flinders Medical Center
Adelaide, Australia
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Fudan University, Shanghai Cancer Center
Shanghai, China
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Hokkaido University Hospital
Hokkaido, Japan
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Kaohsiung Medical University Hospital
Kaohsiung City, Taiwan
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Kumamoto University Hospital
Kumamoto, Japan
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Linkou Chang Gung Memorial Hospital
Linkou District, Taiwan
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National Cancer Center Hospital
Tokyo, Japan
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National Cancer Center Hospital East
Chiba, Japan
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National University Cancer Institute
Singapore, Singapore
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Osaka University Hospital
Osaka, Japan
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Taipei Veterans General Hospital
Taipei, Taiwan
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The Cancer Institute Hospital of JFCR
Tokyo, Japan
Conditions
Explore the condition pages connected to this study.