New drug tarlatamab takes on tough lung cancers

NCT ID NCT07016230

First seen Jun 26, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This phase 2 trial is testing a drug called tarlatamab in 40 people with advanced small-cell lung cancer or other poorly differentiated neuroendocrine cancers. The drug is given by IV and aims to shrink tumors. Researchers will also study blood and tumor samples to understand why some patients respond and others don't.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tarlatamab
What this could lead to
If successful, this could provide a new treatment option for hard-to-treat small-cell lung cancer and related neuroendocrine cancers.
What could go wrong
This is a small, early-phase trial with only 40 participants. The drug may not shrink tumors or could cause serious side effects. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gustave Roussy

    Villejuif, France