New drug combo shows promise in slowing rare sarcoma growth

NCT ID NCT04807816

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding the drug berzosertib to standard chemotherapy (gemcitabine) can help control a rare soft-tissue cancer called leiomyosarcoma. 58 adults with advanced or spreading disease took part. The goal was to see if the combination could stop or shrink tumors for at least 6 months. This is a disease-control approach, not a cure.

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Conditions

The condition(s) this trial relates to.

leiomyosarcoma Neoplasm Metastasis sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Poitiers

    Poitiers, 86000, France

  • Centre Leon Berard

    Lyon, 69008, France

  • IUCT Oncopôle

    Toulouse, 31059, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Gustave Roussy

    Villejuif, 94805, France