New drug combo aims to control aggressive blood disorder

NCT ID NCT03383575

Summary

This study is testing a targeted drug called enasidenib, sometimes combined with another drug (azacitidine), for people with a high-risk type of blood and bone marrow disorder called myelodysplastic syndrome (MDS) that has a specific genetic change (IDH2 mutation). The goal is to see if this approach is safe and can help control the disease by stopping the growth of abnormal cells. The trial will enroll about 63 participants who either haven't tried a certain type of therapy before or whose disease has come back after that therapy.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic Foundation

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44195, United States

  • Johns Hopkins University/Sidney Kimmel Cancer Center

    ACTIVE_NOT_RECRUITING

    Baltimore, Maryland, 21287, United States

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact

Conditions

Explore the condition pages connected to this study.