Blood test may end need for risky vein sampling in adrenal hypertension
NCT ID NCT07297745
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether measuring certain hormones in a blood sample can accurately identify which patients with primary aldosteronism (a common cause of high blood pressure) have a curable adrenal tumor. Currently, diagnosis often requires an invasive procedure called adrenal vein sampling. If the blood test works, it could simplify diagnosis, reduce risks, and help more people get the right treatment. The trial will enroll 120 adults who are willing to undergo both the blood test and standard procedures to compare accuracy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
blood test for hybrid hormones (18-oxocortisol, 18-hydroxycortisol)
What this could lead to
If successful, this could make diagnosing curable adrenal-related high blood pressure faster, cheaper, and less invasive for patients worldwide.
What could go wrong
This is an early-stage diagnostic study with only 120 participants. The blood test may not be accurate enough to replace current invasive methods, and results may not apply to all patient groups.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Other studies related to the condition(s) this trial covers.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Changi General Hospital
Singapore, Singapore, 529889, Singapore
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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National University Hospital
Singapore, Singapore
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sengkang General Hospital
Singapore, Singapore
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Singapore General Hospital
Singapore, Singapore
Contact Phone: •••-•••-•••• Email: •••••@•••••