New cream shows promise for kids with severe eczema

NCT ID NCT05186805

Completed Symptom relief Sponsor: Organon and Co Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested a cream called tapinarof in 36 children aged 2 to 17 with severe eczema covering large areas of skin. The goal was to see how much of the drug gets into the body and whether it is safe. Children applied the cream once daily, and researchers monitored side effects and drug levels.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tapinarof cream, 1%
What this could lead to: If successful, this could point toward a new topical treatment option for children with severe eczema.
What could go wrong: This is a small, early-phase study focused on safety and drug levels, not on proving effectiveness. The cream may not work for all children or could cause skin irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATOPIC DERMATITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atopic eczema Eczema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATOPIC DERMATITIS

Contacts and locations

Locations

Dermavant Investigative Site

Thousand Oaks, California, 91320, United States
Dermavant Investigative Site

Centennial, Colorado, 80112, United States
Dermavant Investigative Site

Coral Gables, Florida, 33146, United States
Dermavant Investigative Site

Hialeah, Florida, 33016, United States
Dermavant Investigative Site

Miami Lakes, Florida, 33014, United States
Dermavant Investigative Site

Chicago, Illinois, 60611, United States
Dermavant Investigative Site

Summerville, South Carolina, 29445, United States
Dermavant Investigative Site

Houston, Texas, 77030, United States
Dermavant Investigative Site

San Antonio, Texas, 78213, United States
Dermavant Investigative Site

Calgary, Alberta, T3A 2N1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.