New cream shows promise for kids with severe eczema
NCT ID NCT05186805
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested a cream called tapinarof in 36 children aged 2 to 17 with severe eczema covering large areas of skin. The goal was to see how much of the drug gets into the body and whether it is safe. Children applied the cream once daily, and researchers monitored side effects and drug levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tapinarof cream, 1%
What this could lead to
If successful, this could point toward a new topical treatment option for children with severe eczema.
What could go wrong
This is a small, early-phase study focused on safety and drug levels, not on proving effectiveness. The cream may not work for all children or could cause skin irritation.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dermavant Investigative Site
Thousand Oaks, California, 91320, United States
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Dermavant Investigative Site
Centennial, Colorado, 80112, United States
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Dermavant Investigative Site
Coral Gables, Florida, 33146, United States
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Dermavant Investigative Site
Hialeah, Florida, 33016, United States
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Dermavant Investigative Site
Miami Lakes, Florida, 33014, United States
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Dermavant Investigative Site
Chicago, Illinois, 60611, United States
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Dermavant Investigative Site
Summerville, South Carolina, 29445, United States
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Dermavant Investigative Site
Houston, Texas, 77030, United States
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Dermavant Investigative Site
San Antonio, Texas, 78213, United States
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Dermavant Investigative Site
Calgary, Alberta, T3A 2N1, Canada