Nerve blocks may offer better pain relief for appendicitis patients in the ER

NCT ID NCT06808087

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two types of nerve blocks (TAP and ESPB) to standard pain medication (tramadol) for people with acute appendicitis in the emergency department. The goal was to see if these blocks could reduce pain before surgery and lower the need for opioids. The trial included 96 adults and was completed at a single hospital in Turkey.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nerve block (TAP block or ESPB block)

What this could lead to

If successful, this could show that nerve blocks are a better way to manage appendicitis pain in the ER, possibly reducing the need for strong painkillers like opioids.

What could go wrong

This is a small, completed study with only 96 participants. The results may not apply to all patients, and nerve blocks carry risks like infection or allergic reaction.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

agnosia appendicitis Emergencies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ankara City Hospital

    Ankara, Yenimahalle, Turkey (Türkiye)