Could a lower tamoxifen dose prevent breast cancer in High-Risk women?
NCT ID NCT06184750
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 32 times
Summary
This study tests a low-dose tamoxifen plan to lower breast density, a key risk factor for breast cancer, in 200 premenopausal women at higher-than-average risk. Participants start on a low dose, and if their breast density doesn't drop enough, the dose is increased. The goal is to find a dose that works with fewer side effects, potentially offering a better prevention option.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Case Western Reserve University
NOT_YET_RECRUITINGCleveland, Ohio, 44106, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Northwestern University
RECRUITINGChicago, Illinois, 60611, United States
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University of Arizona Cancer Center - Prevention Research Clinic
RECRUITINGTucson, Arizona, 85719, United States
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University of Illinois College of Medicine - Chicago
RECRUITINGChicago, Illinois, 60612, United States
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
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University of Michigan Rogel Cancer Center
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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