New shot for immune deficiency shows promise in early trial

NCT ID NCT05755035

First seen Feb 03, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This study tested a new medicine called TAK-881 in 65 people with primary immunodeficiency diseases (PIDD), which make it hard for the body to fight infections. The goal was to see how well the body processes TAK-881 compared to an existing treatment (HYQVIA) and to check its safety. Participants received either TAK-881 or HYQVIA for up to 51 weeks, and younger children received only TAK-881 for up to 27 weeks. The study is complete, and results will help determine if TAK-881 is a safe and effective option for managing PIDD.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aarhus Universitetshospital

    Aarhus, 8200, Denmark

  • Allergy Partners of North Texas

    Dallas, Texas, 75230, United States

  • Allergy and Asthma Clinical Research

    Walnut Creek, California, 94598, United States

  • Central Georgia Infectious Disease Consultants

    Macon, Georgia, 31201, United States

  • Duke Asthma, Allergy and Airway Center

    Durham, North Carolina, 27705, United States

  • Fakultni Nemocnice v Motole

    Prague, 14300, Czechia

  • Fakultni nemocnice u sv. Anny v Brne - ICRC

    Brno, 656 91, Czechia

  • Hospital Sant Joan de Deu Barcelona

    Esplugues de Llobregat, Barcelona, 08950, Spain

  • Instytut Pomnik - Centrum Zdrowia Dziecka

    Warsaw, Masovian Voivodeship, 00-999, Poland

  • Klinika Deti a Dorastu - Odborne Ambulancie UNM a JLF UK Martin

    Martin, 036 01, Slovakia

  • Louisiana State University Health Science Center-New Orleans

    New Orleans, Louisiana, 70118, United States

  • Montefiore Medical Center

    The Bronx, New York, 10461, United States

  • NUDCH (National Institute of Children's Diseases)

    Bratislava, 833 40, Slovakia

  • National Jewish Medical And Research Center

    Denver, Colorado, 80206, United States

  • Northwell Health

    Great Neck, New York, 11021, United States

  • OKIA, s.r.o

    Košice, 040 01, Slovakia

  • Odense University Hospital

    Odense, 5000, Denmark

  • Optimed Research, LTD

    Columbus, Ohio, 43235, United States

  • Osrodek Pediatryczny im. DR J. Korczaka, Wojewodzkie Wielospecjalistyczne Centrum i Traumatologii im. M. Kopernika w Lodzi

    Lodz, 90329, Poland

  • Rush University Medical Center - University Cardiovascular Surgeons

    Chicago, Illinois, 60612-3852, United States

  • Sneeze, Wheeze, & Itch Associates, LLC

    Normal, Illinois, 61761, United States

  • Tanner Clinic

    Murray, Utah, 84107, United States

  • Universitaetsklinikum Tuebingen (UKT)

    Tübingen, 72076, Germany

  • Universitair Medisch Centrum Utrecht (UMC Utrecht)

    Utrecht, 3584 CX, Netherlands

  • University Hospital Brno (Fakultni Nemocnice Brno) - Children's Hospital (Detska nemocnice)

    Brno, 62500, Czechia

  • University Hospital Carl Gustav Carus

    Dresden, 01307, Germany

  • University Hospital La Paz

    Madrid, 28046, Spain

  • University of California Irvine Medical Center

    Irvine, California, 92697, United States

  • University of South Florida

    St. Petersburg, Florida, 33701, United States

  • Uniwersyteckie Centrum Kliniczne, KLINIKA PEDIATRII, HEMATOLOGII I ONKOLOGII

    Gdansk, Pomeranian Voivodeship, 80-952, Poland

  • Vital Prospects Clinical Research Institute, PC

    Tulsa, Oklahoma, 74136, United States

  • Wojskowy Instytut Medyczny,Centralny Szpital Kliniczny Ministerstwa Obronty Narodowej

    Warsaw, Masovian Voivodeship, 04-141, Poland

Conditions

Explore the condition pages connected to this study.