New drug tested to tame debilitating itch in kids with rare liver disease

NCT ID NCT05543187

Summary

This study tested an investigational drug called TAK-625 in Japanese children with a rare, inherited liver disease called PFIC. The main goal was to see if the drug could reduce the severe, life-altering itching caused by the disease and lower harmful bile acid levels in the blood. Five participants received the drug for up to 34 months while researchers monitored their symptoms and safety.

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Contacts and locations

Locations

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, Japan

  • Kyoto University Hospital

    Kyoto, Japan

  • Kyushu University Hospital

    Fukuoka, Japan

  • Osaka University Hospital

    Suita, Osaka, Japan

  • Saitama Prefectural Children's Medical Center

    Saitama, Japan

  • Tsuyama Chuo Hospital

    Tsuyama, Okayama-ken, Japan

  • University of Tsukuba Hospital

    Tsukuba, Ibaraki, Japan

  • Yokohamashi Tobu Hospital

    Yokohama, Kanagawa, Japan

Conditions

Explore the condition pages connected to this study.