New drug shows promise for clearing severe skin plaques
NCT ID NCT06108544
Summary
This large, late-stage study tested whether a new oral drug, TAK-279, could clear or nearly clear the thick, scaly skin patches of moderate-to-severe plaque psoriasis. Over 1,100 participants were randomly assigned to receive TAK-279, a placebo (inactive pill), or an already-approved drug called apremilast for comparison. The main goal was to see how much better TAK-279 worked than the placebo at reducing the severity and extent of psoriasis after 16 weeks.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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4 Medical Clinical Solutions (4MCS) Swinton - PPDS
Ilford, Essex, IG1 4HP, United Kingdom
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AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Gdyni
Gdynia, Pomeranian Voivodeship, 81-537, Poland
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AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Katowicach
Katowice, Silesian Voivodeship, 40-040, Poland
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AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Warszawie
Warsaw, Masovian Voivodeship, 02-672, Poland
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ALLCUTIS Research, LLC.
Portsmouth, New Hampshire, 03801-03804, United States
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AP-HM- Hôpital de La Timone
Marseille, 13885, France
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Accellacare - North London Clinical Studies Centre
Northwood, Middlesex, HA6 2RN, United Kingdom
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Accellacare of Northamptonshire
Harrow, Middlesex, HA1 3UJ, United Kingdom
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Accellacare of Yorkshire
Chorley, Lancashire, PR7 7NA, United Kingdom
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Adoria
Riga, Ohio, LV-1011, Latvia
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Advanced Clinical Research Institute (ACRI) - Florida
Tampa, Florida, 33607-6429, United States
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Advanced Medical Research, PC
Atlanta, Georgia, 30342-1418, United States
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Affiliated Hospital of Jiangsu University
Zhenjiang, Jiangsu, 212001, China
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Alberta DermaSurgery Centre - Probity - PPDS
Edmonton, Alberta, T6G 1C2 Canada, Canada
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Allcutis Research LLC
Beverly, Massachusetts, 01915, United States
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Allergo-Derm Bakos Kft- Szolnok-Baross utca 20
Szolnok, Jász-Nagykun-Szolnok, 5000, Hungary
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Alliance Clinical Trials - Probity - PPDS
Waterloo, Ontario, N2J 1C4, Canada
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Ambulatorium Barbara Bazela
Elblag, 82-300, Poland
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Ambulatory for Specialized Medical Care- Group Practice in Dermatology - Clinic EuroDerma OOD
Sofia, Sofia-Grad, 1606, Bulgaria
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Apex Clinical Research Center
Mayfield Heights, Ohio, 44124-4005, United States
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Arlington Research Center
Arlington, Texas, 76011-3800, United States
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Austin Institute for Clinical Research, Inc. - Pflugerville - ClinEdge - PPDS
Pflugerville, Texas, 78660-6148, United States
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Beacon Clinical Research LLC
Brockton, Massachusetts, 02301, United States
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Brunswick Dermatology Centre - Probity - PPDS
Fredericton, New Brunswick, E3B 1G9, Canada
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Burke Pharmaceutical Research
Hot Springs, Arkansas, 71913-6475, United States
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CCR Ostrava s.r.o.
Ostrava, Moravskoslezský kraj, 702 00, Czechia
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CLINTRIAL s.r.o.
Prague, Praha, Hlavní Mesto, 100 00, Czechia
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CaRe Clinic-Red Deer
Red Deer, Alberta, T4N 7C3, Canada
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Cahaba Dermatology Skin Health Center
Hoover, Alabama, 35244-2111, United States
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Canadian Dermatology Centre - Probity - PPDS
Toronto, Ontario, M3B 0A7, Canada
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Center For Clinical Studies, LTD. LLP - 451 N Texas Ave
Webster, Texas, 77598-4927, United States
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Center For Clinical Studies,LTD. LLP - 451 N Texas Ave
Webster, Texas, 77598-4927, United States
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Centre For Dermatology and Cosmetic Surgery - Probity - PPDS
Richmond Hill, Ontario, L4B 1M5, Canada
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Centre Hospitalier Le Mans
Le Mans, Ohio, 72037, France
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Centro de Investigacion Clínica - CEDIC
Ciudad Autónomade Buenos Aires, C1060ABN, Argentina
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Centro de Investigaciones Médicas Tucumán - PPDS
San Miguel de Tucumán, T4000, Argentina
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Centrum Badan Klinicznych PI-House sp. z o.o.
Gdansk, Pomeranian Voivodeship, 80-546, Poland
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Centrum Medyczne ALL-MED
Krakow, Lesser Poland Voivodeship, 30-033, Poland
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Centrum Medyczne Angelius Provita
Katowice, Silesian Voivodeship, 40-611, Poland
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Centrum Medyczne Chojnice - PRATIA - PPDS
Chojnice, Pomeranian Voivodeship, 89-600, Poland
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Centrum Terapii Wspolczesnej
Lódz, Lódzkie, 90-338, Poland
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Centrum Uslug Medycznych MaxMed
Bochnia, 32-700, Poland
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China-Japan Friendship Hospital
Beijing, Beijing Municipality, 100029, China
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ClinMedica Research
Skierniewice, Lódzkie, 96-100, Poland
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ClinOhio Research Services
Columbus, Ohio, 43213-4445, United States
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Clinical Research Group Sp. z o.o
Warsaw, Masovian Voivodeship, 01-142, Poland
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Conexa Investigación Clínica S.A.
Buenos Aires, C1012, Argentina
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Cumberland Skin Center for Clinical Research - Objective Health - PPDS
Hermitage, Tennessee, 37076-3497, United States
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DS Research - 1005 E. Lewis & Clark Pkwy Indiana Location
Clarksville, Indiana, 47129-2201, United States
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DS Research of Kentucky
Louisville, Kentucky, 40241-6162, United States
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David Fivenson MD Dermatology PLLC
Ann Arbor, Michigan, 48103-9746, United States
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Debreceni Egyetem Klinikai Kozpont Nagyerdei Campus
Debrecen, Hajdú-Bihar, 4032, Hungary
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Derm Research Center of NY
Stony Brook, New York, 11790, United States
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DermEdge Research - Probity - PPDS
Mississauga, Ontario, L4Y 4C5, Canada
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DermEffects - Probity - PPDS
London, Ontario, N6H 5L5, Canada
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Dermamedica, s.r.o. - Kozni Ambulance Nachod
Náchod, Královéhradecký kraj, 547 01, Czechia
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Dermatologikum Hamburg
Hamburg, 20354, Germany
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Dermatology & Advanced Aesthetics
Lake Charles, Louisiana, 70605-1213, United States
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Dermatology Clinical Research Center of San Antonio
San Antonio, Texas, 78229-3409, United States
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Dermatology Institute and Skin Care Center
Santa Monica, California, 90404-2216, United States
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Dermatology Research Institute, Inc. - Probity - PPDS
Calgary, Alberta, T3A 2N1, Canada
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Dermatrials Research
Hamilton, Ontario, L8N 1Y2, Canada
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Dermedic Jacek Zdybski
Ostrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland
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DermoDent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski, s.c.
Osielsko, 86-031, Poland
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Dermskin s.r.o.
Olomouc, Olomoucký kraj, 779 00, Czechia
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Diagnostic Consultative Center Sveti Georgi EOOD
Haskovo, 6300, Bulgaria
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Diagnostic Consultative Center XXVIII - Sofia - EOOD
Sofia, Sofia-Grad, 1592, Bulgaria
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Diagnostic Consultative Centre - Focus-5 - LZIP EOOD
Sofia, Sofia-Grad, 1463, Bulgaria
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Diagnostic and Consulting Center Aleksandrovska EOOD
Sofia, Sofia-Grad, 1431, Bulgaria
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Diamond Clinic
Krakow, 31-559, Poland
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Divine Dermatology and Aesthetics, LLC
Atlanta, Georgia, 30315-2042, United States
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Dr. S. K. Siddha Medicine Professional Corporation - Probity - PPDS
Richmond Hill, Ontario, L4C 9M7, Canada
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Duke Dermatology Clinic
Durham, North Carolina, 27710-4000, United States
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ETG Lublin - PPDS
Lublin, 20-314, Poland
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ETG Siedlce - PPDS
Siedlce, Masovian Voivodeship, 08-110, Poland
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ETG Warszawa - PPDS
Warsaw, Masovian Voivodeship, 02-677, Poland
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ETYKA Osrodek Badan Klinicznych
Olsztyn, 10-117, Poland
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FXM Research Miramar
Miramar, Florida, 33027-4714, United States
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Fachklinik Bad Bentheim
Bad Bentheim, Lower Saxony, 48455, Germany
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Fakultni nemocnice Kralovske Vinohrady
Prague, 100 34, Czechia
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First Hospital of Shanxi Medical University
Taiyuan, Shanxi, 030001, China
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First OC Dermatology Research Inc.
Fountain Valley, California, 92708-3701, United States
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Florida Academic Centers Research
Miami, Florida, 33136-1003, United States
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FutureMeds - Berlin - PPDS
Berlin, 10629, Germany
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FutureMeds - Targowek - PPDS
Warsaw, Masovian Voivodeship, 03-291, Poland
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GCM Medical Group, PSC -62 Calle Jose Marti
San Juan, 00909-3004, Puerto Rico
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Globe Badania Kliniczne Spólka z o.o. - Klodzko
Klodzko Dolnoslaskie, 57-300, Poland
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Guangdong Provincial People's Hospital
Guangzhou, Guangdong, 510080, China
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HaEmek Medical Center
Afula, 18101, Israel
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Hadassah Medical Center- Ein Kerem - PPDS
Jerusalem, Jerusalem, 9112002, Israel
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Health Center 4, Center of Diagnostics
Riga, LV-1003, Latvia
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Health Center 4, Clinic of Dermatology
Riga, LV-1013, Latvia
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Henan Provincial People's Hospital
Zhengzhou, Henan, 450003, China
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Hospital A.Syggros
Athens, Attica, 161 21, Greece
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Hospital Clinico San Carlos
Madrid, 28040, Spain
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Hospital Of Skin And Venereal Diseases of Thessaloniki
Thessaloniki, 546 43, Greece
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Hospital Universitario Germans Trias i Pujol
Badalona, Barcelona, 08915, Spain
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Hospital Universitario La Paz - PPDS
Madrid, 28046, Spain
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Hospital Universitario de Gran Canaria Doctor Negrin
Las Palmas de Gran Canaria, 35010, Spain
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Hospital de La Santa Creu i Sant Pau
Barcelona, 08041, Spain
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Hospital de Manises
Manises, Valencia, 46940, Spain
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Houston Center for Clinical Research, LLC
Sugar Land, Texas, 77479-1001, United States
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Huashan Hospital Fudan University - PPDS
Shanghai, 200040, China
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Hôpital Charles Nicolle-1 Rue de Germont
Rouen, 76031, France
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Instituto de Neumonologia y Dermatologia
Buenos Aires, C1425BEA, Argentina
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J. Kisis
Riga, LV-1003, Latvia
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Johnson Dermatology Clinic
Fort Smith, Arkansas, 72916-6103, United States
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Klinische Forschung Dresden GmbH (KFGN) - PRATIA - PPDS
Dresden, Saxony, 01069, Germany
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Krakowskie Centrum Medyczne - FutureMeds - PPDS
Krakow, Lesser Poland Voivodeship, 31-501, Poland
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Lawrence J Green, MD LLC
Rockville, Maryland, 20850-6363, United States
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Lenus Research & Medical Group
Sweetwater, Florida, 33172-2741, United States
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Lima's Excellence In Allergy And Dermatology Research (Leader) Inc. - Probity - PPDS
Hamilton, Ontario, L8L 3C3, Canada
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Long Beach Research Institute, LLC
Long Beach, California, 90805-4587, United States
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Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska
Lublin, Lublin Voivodeship, 20-573, Poland
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Lynderm Research Inc - Probity - PPDS
Markham, Ontario, L3P 1X3, Canada
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MBAL Skin Systems, Doganovo
Elin Pelin, Sofia, 2115, Bulgaria
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MC Comac Medical - IRN - PPDS
Sofia, Sofia-Grad, 1612, Bulgaria
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MCM Krakow - PRATIA - PPDS
Krakow, 30-727, Poland
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MICS Centrum Medyczne Torun - MICS - PPDS
Torun, Ohio, 87-100, Poland
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Medical Center Asklepii OOD
Dupnitsa, Kyustendil, 2600, Bulgaria
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Medical Center Exacta Medica - Vasil Levski 60
Pleven, 5801, Bulgaria
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Medical Center Hera EOOD
Sofia, Sofia-Grad, 1510, Bulgaria
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Medical Center Medconsult Pleven OOD
Pleven, 5800, Bulgaria
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Medical Center Unimed EOOD
Sevlievo, Gabrovo, 5400, Bulgaria
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Medical Dermatology Specialists
Phoenix, Arizona, 85006-2722, United States
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Medizinisches Versorgungszentrum DermaKiel GmbH
Kiel, 24148, Germany
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Metropolis Dermatology Downtown LA - Probity - PPDS
Los Angeles, California, 90017-5310, United States
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Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia
Sofia, Sofia-Grad, 1606, Bulgaria
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Minnesota Clinical Study Center
Fridley, Minnesota, 55432-3134, United States
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Modern Research Associates
Dallas, Texas, 75231-6077, United States
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Montefiore Dermatology - BRANY - PPDS
The Bronx, New York, 10467-1402, United States
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Mount Sinai Doctors -234 E 85th St
New York, New York, 10029-6504, United States
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Multiprofile Hospital For Active Treatment Dr Tota Venkova
Gabrovo, 5300, Bulgaria
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Multiprofile Hospital for Active Treatment - Dobrich AD
Dobrich, 9300, Bulgaria
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NZOZ Osteo Medic SC Artur Racewicz Jerzy Supronik
Bialystok, Podlaskie Voivodeship, 15-351, Poland
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Nemocnice AGEL Novy Jicin a.s
Nový Jičín, Moravskoslezský kraj, 741 01, Czechia
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Noble Clinical Research
Tucson, Arizona, 85704-7892, United States
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North Texas Center for Clinical Research
Frisco, Texas, 75034, United States
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NorthShore Medical Group Dermatology - Skokie
Skokie, Illinois, 60077-1049, United States
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Northridge Clinical Trials
Northridge, California, 91325-4122, United States
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Oakland Hills Dermatology - 3400 Auburn Rd
Auburn Hills, Michigan, 48326-3396, United States
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Olympian Clinical Research - 6331 Memorial Hwy
Tampa, Florida, 33615, United States
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Oregon Medical Research Center PC
Portland, Oregon, 97239-4501, United States
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Oshawa Clinic-117 King St
Oshawa, Ontario, L1R 1R7, Canada
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Ostrowieckie Centrum Medyczne
Ostrowiec Świętokrzyski, Świętokrzyskie Voivodeship, 27-400, Poland
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Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 564 29, Greece
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Praglandia s.r.o.
Prague, Ohio, 150 00, Czechia
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Pratia Brno s.r.o. - PRATIA - PPDS
Brno, South Moravian, 602 00, Czechia
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Pratia Pardubice a.s. - PRATIA - PPDS
Pardubice, 530 02, Czechia
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Praxis fur Dermatologie and Venerologie
Dresden, Saxony, 01097, Germany
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Pro Familia Altera Sp. z o.o.
Katowice, Silesian Voivodeship, 40-648, Poland
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Prof. MUDr. Petr Arenberger, DrSc. - CRC - PPDS
Prague, 110 00, Czechia
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Psoriasis Treatment Center of Central New Jersey
East Windsor, New Jersey, 08520, United States
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Pécsi Tudomanyegyetem - Vasvari Pal u.
Pécs, 7632, Hungary
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RCMed Oddzial Sochaczew
Sochaczew, Masovian Voivodeship, 96-500, Poland
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Rabin Medical Center - PPDS
Petah Tikva, 49100, Israel
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Revival Research Corporation - Florida - ClinEdge - PPDS
Doral, Florida, 33122-1902, United States
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Riga 1st Hospital
Riga, LV-1001, Latvia
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Royalderm
Warsaw, Poland
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SKiN Centre for Dermatology - Peterborough - Probity - PPDS
Peterborough, Ontario, K9J 1Z2, Canada
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SRH Wald-Klinikum Gera GmbH
Gera, Thuringia, 07548, Germany
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STAT Research S.A.
Buenos Aires, C1023AAB, Argentina
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Sadick Research Group
New York, New York, 10075-0385, United States
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Salford Royal Hospital - PPDS
Salford, Lancashire, M6 8HD, United Kingdom
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San Marcus Research Clinic Inc
Miami Lakes, Florida, 33014-5602, United States
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Semigallia
Kuldīga, LV-3301, Latvia
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Siena Medical Research
Westmount, Quebec, H3Z 2S6, Canada
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Sir Run Run Shaw Hospital Zhejiang University School of Medicine - Qingchun Campus
Hangzhou, Zhejiang, 310016, China
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Skin Care Physicians of Georgia
Macon, Georgia, 31217-3861, United States
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Skin Sciences, PLLC
Louisville, Kentucky, 40217-1444, United States
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Skin Specialists PC
Omaha, Nebraska, 68144, United States
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Skinsense Medical Research - 411 2nd Ave N - Probity - PPDS
Saskatoon, Saskatchewan, S7K 0H6, Canada
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Smite Aija doctor practice in dermatology, venerology
Talsi, Talsu Aprinkis, LV-3201, Latvia
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Solumed Centrum Medyczne
Poznan, Greater Poland Voivodeship, 60-101, Poland
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Somogy Varmegyei Kaposi Mor Oktato Korhaz
Kaposvár, Somogy County, 7400, Hungary
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St Luke's Hospital
Bradford, West Yorkshire, BD5 0NA, United Kingdom
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Szegedi Tudomanyegyetem
Szeged, Csongrád megye, 6720, Hungary
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TCR Medical Corporation
San Diego, California, 92123-1523, United States
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Tel Aviv Sourasky Medical Center Ichilov - PPDS 27004
Tel Aviv, Tel Aviv, 64239, Israel
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Tennessee Clinical Research Center
Nashville, Tennessee, 37215-2888, United States
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Texas Dermatology and Laser Specialists
San Antonio, Texas, 78218-3128, United States
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The Centre for Clinical Trials Inc. - Probity - PPDS
Oakville, Ontario, L6J 7W5, Canada
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The Chaim Sheba Medical Center - PPDS
Ramat Gan, Tel Aviv, 52621, Israel
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The First Affiliated Hospital With Nanjing Medical University(Jiangsu Province Hospital)
Nanjing, Jiangsu, 210029, China
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The Second Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, 650000, China
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The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330008, China
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The Skin Surgery Center for Clinical Research - Objective Health - PPDS
Winston-Salem, North Carolina, 27103-7109, United States
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The Third Xiangya Hospital of Central South University
Changsha, Hunan, 410013, China
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Tongji Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
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Toronto Research Centre - Probity - PPDS
Toronto, Ontario, M3H 5Y8, Canada
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Total Dermatology
Birmingham, Alabama, 35205, United States
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Twoja Przychodnia Nowosolskie Centrum Medyczne sp. z o.o
Nowa Sól, Lubusz Voivodeship, 67-100, Poland
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Twoja Przychodnia PCM
Poznan, Greater Poland Voivodeship, 61-293, Poland
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UNISON Clinical Trials (Shahram Jacobs md inc.)
Encino, California, 91436-2428, United States
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UT Physicians Dermatology - Bellaire Station
Bellaire, Texas, 77401-3535, United States
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University Clinical Trials
San Diego, California, 92123, United States
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University General Hospital ''ATTIKON''
Chaïdári, Attica, 124 62, Greece
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University Hospital of Ioannina
Loannina, Loannina, 455 00, Greece
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University Multiprofile Hospital for Active Treatment -Dr. Georgi Stranski -Gen. V. Vazov Str 91
Pleven, Bulgaria
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University of Michigan Hospital - 1500 E Medical Center Dr
Ann Arbor, Michigan, 48109-5360, United States
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University of Pittsburgh Medical Center-3601 5th Ave
Pittsburgh, Pennsylvania, 15213-3403, United States
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VIDA Dermatology - Probity - PPDS
Edmonton, Alberta, T6H 4J8, Canada
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Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz
Szombathely, Vas County, 9700, Hungary
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Velocity Clinical Research, High Wycombe - PPDS
High Wycombe, Buckinghamshire, HP11 2QW, United Kingdom
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Velocity Clinical Research, North London - PPDS
London, Middlesex, N12 8BU, United Kingdom
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Veseliba un estetika
Riga, LV-1009, Latvia
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Virginia Clinical Research - 6160 Kempsville Cir
Norfolk, Virginia, 23507, United States
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Vivida Dermatology - Flamingo Rd - Probity - PPDS
Las Vegas, Nevada, 89119-5190, United States
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Wake Forest Baptist Health Department of Dermatology - 4618 Country Club Rd
Winston-Salem, North Carolina, 27157-0001, United States
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West China Hospital Sichuan University
Chengdu, Sichuan, 610041, China
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Whipps Cross Hospital
London, London, City of, E11 1NR, United Kingdom
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Wiseman Dermatology Research Inc. - Probity - PPDS
Winnipeg, Manitoba, R3E 0V9, Canada
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Wright State Physicians
Fairborn, Ohio, 45324, United States
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WroMedica
Wroclaw, Lower Silesian Voivodeship, 51-685, Poland
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XLR8 Medical Research - Probity - PPDS
Windsor, Ontario, N8X 3V6, Canada
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Zenith Research, Inc.
Beverly Hills, California, 90211-1705, United States
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dermMEDICA Sp. z o.o
Wroclaw, 51-503, Poland
Conditions
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