New cell therapy TAK-007 tested in lymphoma patients who have run out of options
NCT ID NCT05020015
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing an experimental cell therapy called TAK-007 in 27 adults with B-cell non-Hodgkin lymphoma that has come back or not responded to treatment. Participants first receive chemotherapy to lower certain white blood cells, then get one or three injections of TAK-007. The study is checking for side effects and whether the lymphoma shrinks or disappears.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- TAK-007 (a cell therapy) given as an injection after chemotherapy
- What this could lead to
- If successful, this could offer a new treatment option for people with B-cell non-Hodgkin lymphoma that has not responded to other therapies.
- What could go wrong
- This is a small, early-phase trial with only 27 participants, so results may not apply to everyone. Side effects from the cell therapy or chemotherapy could be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cedars Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute
Los Angeles, California, 90048, United States
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Columbia University Medical Center
New York, New York, 10032, United States
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DUHS Duke Blood Cancer Center
Durham, North Carolina, 27705, United States
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MedStar Georgetown University Medical Center
Washington D.C., District of Columbia, 20007, United States
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Montefiore Medical Center
The Bronx, New York, 10467, United States
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Northside Hospital
Atlanta, Georgia, 30342, United States
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Northwestern Memorial Hospital
Chicago, Illinois, 60611, United States
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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Saint Davids South Austin Medical Center
Austin, Texas, 78704, United States
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Sylvester Comprehensive Cancer Center University of Miami Hospitals and Clinics
Miami, Florida, 33136, United States
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Thomas Jefferson University Sidney Kimmer Cancer Center, Clinical Research Organization
Philadelphia, Pennsylvania, 19107, United States
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University of Alabama at Birmingham
Birmingham, Alabama, 35249, United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Virginia Comprehensive Cancer Center
Charlottesville, Virginia, 22903, United States