Shorter blood thinner combo may cut bleeding risk in heart patients
NCT ID NCT05418556
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times
Summary
This study tests whether a personalized blood-thinner plan can reduce bleeding in people with coronary artery disease who have received a heart stent. About 3,944 participants will either get the usual dual antiplatelet therapy (two blood thinners) or a shorter course followed by just one drug. The goal is to see if the tailored approach causes less bleeding while still preventing heart attacks and stent problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- aspirin, clopidogrel, prasugrel, ticagrelor
- What this could lead to
- If successful, this could lead to a safer antiplatelet strategy that lowers bleeding risk while still preventing heart attacks and stent blockages.
- What could go wrong
- This is a Phase 4 trial, so the drugs are already approved, but the tailored approach may not prove safer or could increase the risk of blood clots. Results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ajou University Hospital
RECRUITINGSuwon, South Korea
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Asan Medical Center
RECRUITINGSeoul, South Korea
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Bucheon Sejong Hospital
RECRUITINGBucheon-si, South Korea
-
Chungbuk National University Hospital
RECRUITINGChungju, South Korea
-
Chungnam National University Hospital
RECRUITINGJungnam, South Korea
-
Chungnam National University Sejong Hospital
RECRUITINGJungnam, South Korea
-
Daegu Catholic Univ Medical Center
NOT_YET_RECRUITINGDaegu, South Korea
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Dankook University Hospital
RECRUITINGJungnam, South Korea
-
Dong-A University Hospital
RECRUITINGBusan, South Korea
-
Dongkang Hospital
NOT_YET_RECRUITINGUlsan, South Korea
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Gangneung Asan Hospital
RECRUITINGGangneung, South Korea
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Gyeongsang National University Changwon Hospital
RECRUITINGChangwon, South Korea
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Gyeongsang National University Hospital
RECRUITINGJinju, South Korea
-
Hallym Univ. Medical Center.
NOT_YET_RECRUITINGHwaseong-si, South Korea
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Inje University Busan Paik Hospital
NOT_YET_RECRUITINGBusan, South Korea
-
Inje University Haeundae Paik Hospital
NOT_YET_RECRUITINGBusan, South Korea
-
Jeju National University Hospital
RECRUITINGJeju City, South Korea
-
Jeonbuk National University Hospital
RECRUITINGJeonju, South Korea
-
Kangbuk Samsung Hospital
RECRUITINGSeoul, South Korea
-
Kangwon National University Hospital
RECRUITINGChuncheon, South Korea
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Keimyung University Dongsan Medical Center
RECRUITINGDaegu, South Korea
-
Korea University Anam Hospital
RECRUITINGSeoul, South Korea
-
Kosin University Gospel Hospital
RECRUITINGBusan, South Korea
-
Kyungpook National University Hospital
RECRUITINGDaegu, South Korea
-
Pusan National University Yangsan Hospital
NOT_YET_RECRUITINGYangsan, South Korea
-
The Catholic University of Korea, Daejeon ST. Mary's Hospital
RECRUITINGDaejeon, South Korea
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The Catholic University of Korea, Eunpyeong St. Mary's Hospital
RECRUITINGSeoul, South Korea
-
The Catholic University of Korea, ST. Vincent's Hospital
COMPLETEDSuwon, South Korea
-
The Catholic University of Korea, Uijeongbu ST. Mary's Hospital
NOT_YET_RECRUITINGUijeongbu-si, South Korea
-
Ulsan University Hospital
RECRUITINGUlsan, South Korea
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Veterans Hospital
RECRUITINGDaegu, South Korea
-
Veterans Hospital Service Medical Center
RECRUITINGSeoul, South Korea
-
dongguk University Medical Center
NOT_YET_RECRUITINGIlsan, South Korea
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Other studies related to the condition(s) this trial covers.
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