New drug duo aims to tackle Transplant-Related lymphoma
NCT ID NCT05786040
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether combining two antibody drugs, tafasitamab and rituximab, can effectively treat a type of lymphoma that sometimes occurs after an organ transplant. About 28 adults who have developed this condition will receive the drug combination. The main goal is to see how many patients achieve a complete remission of their cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tafasitamab and rituximab (monoclonal antibodies)
- What this could lead to
- If successful, this combination could offer a more effective first-line treatment for post-transplant lymphoma, potentially improving remission rates without increasing toxicity.
- What could go wrong
- This is a small, early-phase (Phase II) trial with only 28 participants, so results may not apply broadly. The drugs may cause side effects like infusion reactions or infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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Rutgers Cancer Institute of New Jersey
RECRUITINGNew Brunswick, New Jersey, 08903, United States
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University of North Carolina-Hillsborough Campus
RECRUITINGHillsborough, North Carolina, 27278, United States
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