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New drug combo offers hope for lymphoma patients who Can't have transplant

NCT ID NCT05429268

Ongoing Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jan 06, 2026 · Last updated May 16, 2026 · Updated 24 times

Summary

This study tests a combination of two drugs, tafasitamab and lenalidomide, in adults with diffuse large B-cell lymphoma that has come back or not responded to previous treatments. Participants must have had 1 to 3 prior treatments and cannot receive high-dose chemotherapy with a stem cell transplant. The main goal is to see how many people's tumors shrink or disappear.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aarhus University Hospital

    Aarhus, 08200, Denmark

  • Acibadem Cityclinica Mhat Tokuda

    Sofia, 01407, Bulgaria

  • Akershus University Hospital

    Lorenskog, 01478, Norway

  • Ankara University Medical Faculty

    Ankara, 06629, Turkey (Türkiye)

  • Antrim Area Hospital Northern Health Social Care Trust

    Antrim, BT41 2RL, United Kingdom

  • Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaza

    Szeged, 06725, Hungary

  • Belfast Health and Social Care Trust, of Trust Headquarters

    Belfast, BT9 7AB, United Kingdom

  • Bon Secours Hospital

    Cork, T12 DV56, Ireland

  • Clinic For Hematology, University Clinical Center Serbia

    Belgrade, 11000, Serbia

  • Clinic of Hematology Clinical Center of Vojvodina

    Novi Sad, 21000, Serbia

  • Clinical Center Kragujevac

    Kragujevac, 34000, Serbia

  • Clinical Hospital Dubrava

    Zagreb, 10000, Croatia

  • Clinical Hospital Merkur

    Zagreb, 10000, Croatia

  • Coltea Clinical Hospital

    Bucharest, 30167, Romania

  • Dr. Abdurrahman Yurtaslan Onkology Teaching and Research Hospitalerciyes Universitesi Tip Faklutesi

    Yenimahalle, 06200, Turkey (Türkiye)

  • Ege University Hospital

    Izmir, 35040, Turkey (Türkiye)

  • Ercyes University Medical School

    Kayseri, 38039, Turkey (Türkiye)

  • Fakultni Nemocnice Olomouc

    Olomouc, 779 00, Czechia

  • Gazi University Hospital Gazi University Faculty of Medicine

    Ankara, 06560, Turkey (Türkiye)

  • Hacettepe University Cancer Institute Clinical Oncology Department

    Ankara, 06230, Turkey (Türkiye)

  • Hadassah University Hospital

    Jerusalem, 92210, Israel

  • Helsinki University Central Hospital

    Helsinki, FI-00029, Finland

  • Institute For Pulmonary Diseases of Vojvodina

    Kamenitz, 21204, Serbia

  • Institutul Oncologic Prof. Dr. Ion Chiricuta Cluj-Napoca

    Cluj-Napoca, 400015, Romania

  • Institutul Regional de Oncologie Iasi

    Iași, 700483, Romania

  • Kuopio University Hospital

    Kuopio, 70210, Finland

  • Maria Sklodowska-Curie National Research Institute of Oncology

    Warsaw, 02-0781, Poland

  • Markhot Ferenc Korhaz

    Eger, 03300, Hungary

  • Marmara Universitesi Pendik Egitim

    Istanbul, 34899, Turkey (Türkiye)

  • Mater Misericordiae University Hospital

    Dublin, D07AX57, Ireland

  • Medical University Plovdiv

    Plovdiv, 04000, Bulgaria

  • Medical University of Gdansk

    Gdansk, 80-211, Poland

  • Meir Medical Center

    Kefar Sava, 44281, Israel

  • Mersin University Medical Faculty

    Mersin, 33000, Turkey (Türkiye)

  • National Institute of Oncology

    Budapest, 01122, Hungary

  • Oddzia Kliniczny Hematologii

    Olsztyn, 10-228, Poland

  • Odense University Hospital

    Odense, 05000, Denmark

  • Oulu University Hospital

    Oulu, 90420, Finland

  • Ozel Liv Hospital Onkoloji Klinigi

    Ankara, 06680, Turkey (Türkiye)

  • Pratia Poznan

    Skórzewo, 60-185, Poland

  • Rambam Health Care Campus

    Haifa, 31096, Israel

  • Semmelweis Egyetem

    Budapest, 01088, Hungary

  • Shaare Zedek Mc

    Jerusalem, 9103102, Israel

  • Somogy Medyei Kaposi Mor Oktato Korhaz

    Kaposvár, 07400, Hungary

  • Specialized Hospital For Active Treatment of Oncological Diseases - Sofia District Eood

    Sofia, 01756, Bulgaria

  • Spitalul Clinic Judetean de Urgenta Targu Mures

    Târgu Mureş, 540136, Romania

  • Szpital Morski Im. Pck Sp. Z O.O

    Gdynia, 81-519, Poland

  • Szpital Uniwersytecki Nr 2 Im Dr. Jana Biziela

    Bydgoszcz, 85-168, Poland

  • Tampere University Hospital

    Tampere, 33520, Finland

  • Tekrda-Nk Tp Fakltesi

    Center, 59030, Turkey (Türkiye)

  • Turku University Hospital

    Turku, 20520, Finland

  • Umhat Alexandrovska Sofia

    Sofia, 01431, Bulgaria

  • Umhat Sv. Ivan Rilski Ead

    Sofia, 01431, Bulgaria

  • Universitetssykehuset I Trondheim - St. Olavs Hospital

    Trondheim, 07006, Norway

  • University Hospital Centre Zagreb

    Zagreb, 10000, Croatia

  • University Hospital Galway

    Galway, H91 YR71, Ireland

  • University Public Hospital Nr 1

    Lublin, 20-081, Poland

  • University of Debrecen

    Debrecen, 04032, Hungary

  • Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego

    Wroclaw, 50-367, Poland

  • Vkf American Hospital

    Istanbul, 34365, Turkey (Türkiye)

  • Vseobecna Fakultni Nemocnice

    Prague, 128 00, Czechia

Conditions

Explore the condition pages connected to this study.

DIFFUSE LARGE B CELL LYMPHOMA LARGE B-CELL LYMPHOMA