Can a drug protect heart transplant patients from ongoing nerve and gut damage?
NCT ID NCT05489523
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 20 times
Summary
This study is for people who have had a heart transplant due to ATTR amyloidosis, a disease that causes abnormal protein buildup. Even after a new heart, the disease can still damage nerves and the digestive system. Researchers want to see if the drug tafamidis can safely slow or stop that damage. About 25 participants will take tafamidis for 12 months while doctors monitor protein levels, nerve function, and side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cedars-Sinai
RECRUITINGBeverly Hills, California, 90211, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Columbia University Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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UT Southwestern Medical Center
RECRUITINGDallas, Texas, 75390, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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