Could a common ED drug help fontan patients? major trial underway

NCT ID NCT05206955

First seen Nov 15, 2025 · Last updated May 13, 2026 · Updated 16 times

Summary

This study tests whether tadalafil, a drug that relaxes blood vessels, can improve blood flow and organ function in adults who had Fontan surgery for a single-ventricle heart defect. About 80 participants will receive either tadalafil or a placebo for several months. The goal is to see if the drug helps the heart pump more efficiently and protects the liver and kidneys from damage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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