Heart shield for breast cancer patients: Beta-Blocker may prevent Chemo-Induced damage
NCT ID NCT03879629
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether the beta-blocker carvedilol can prevent or treat heart problems in breast cancer patients receiving HER2-targeted therapy. About 184 adults with HER2-positive breast cancer will be randomly assigned to take carvedilol either preventatively or only after signs of heart injury appear. The goal is to find the best timing and duration for heart protection during cancer treatment.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Mayo Clinic
Phoenix, Arizona, 85054, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Washington University in St. Louis
St Louis, Missouri, 63110, United States