Brain zaps at personal brain rhythms may sharpen memory in schizophrenia

NCT ID NCT07701343

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study tests whether a gentle, non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve working memory in people with schizophrenia. Thirty participants receive both real and sham stimulation in separate sessions while performing a memory task. The stimulation is personalized to each person's natural brain rhythm and targets areas involved in memory.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
transcranial alternating current stimulation (tACS) — a non-invasive brain stimulation device delivering weak electrical currents at individual alpha frequency to the scalp during a working memory task
What this could lead to
If effective, this approach could offer a non-drug, brain-stimulation method to improve working memory in schizophrenia, potentially enhancing daily functioning.
What could go wrong
This is a small, early-stage trial with only 30 participants and single sessions, so results may not generalize or show lasting benefit. The effect may be subtle or absent.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, 410011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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