Can a Bladder-Directed biologic outsmart Treatment-Resistant bladder cancer?

NCT ID NCT06971614

NEW Recruiting now Disease control Sponsor: ImmVira Pharma Co. Ltd Source: ClinicalTrials.gov ↗

First seen Aug 18, 2026 · Last updated Aug 18, 2026

Summary

This phase II trial is testing an experimental biologic called T3011, given directly into the bladder, for people with high-risk non-muscle-invasive bladder cancer that has not responded to BCG therapy or chemotherapy. The study aims to see if this treatment can shrink or eliminate tumors and delay cancer recurrence. Participants will receive regular bladder instillations of T3011 and be monitored closely for safety and effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: T3011, an experimental biologic given directly into the bladder
What this could lead to: If successful, this could offer a new treatment option for people with high-risk bladder cancer that has not responded to standard therapies, potentially delaying or avoiding bladder removal surgery.
What could go wrong: This is an early-phase (II) trial, so the treatment may not work for everyone or could cause significant side effects. The results will need confirmation in larger studies before it becomes widely available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NONMUSCLE-INVASIVE BLADDER CANCER

Contacts and locations

Locations

Advent Health Medical Group Urology
RECRUITING

Orlando, Florida, 32803, United States
Allegheny Health Network
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Carolina Urologic Research Center
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
East Valley Urology Center
RECRUITING

Queen Creek, Arizona, 85140, United States
Florida Urology Partners, LLP
RECRUITING

Tampa, Florida, 33615, United States
Helios Clinical Research
RECRUITING

Middleburg Heights, Ohio, 44130, United States
Rutgers Cancer Institute
RECRUITING

New Brunswick, New Jersey, 08901, United States
Tower Urology
RECRUITING

Los Angeles, California, 90048, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45267, United States

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