New hope for a common breast cancer type: targeted drug trial aims to outperform chemo

NCT ID NCT04494425

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is for people with advanced breast cancer that is hormone-positive and has low levels of a protein called HER2. It compares a newer, targeted drug (trastuzumab deruxtecan) against standard chemotherapy chosen by the doctor. The main goal is to see if the targeted drug helps patients live longer without their cancer getting worse and improves their quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Locations

Research Site

Scottsdale, Arizona, 85259, United States
Research Site

Springdale, Arkansas, 72762, United States
Research Site

Duarte, California, 91010, United States
Research Site

Los Angeles, California, 90017, United States
Research Site

Aurora, Colorado, 80045, United States
Research Site

Lakewood, Colorado, 80228, United States
Research Site

Washington D.C., District of Columbia, 20016, United States
Research Site

Jacksonville, Florida, 32224, United States
Research Site

Kansas City, Kansas, 66160, United States
Research Site

Louisville, Kentucky, 40202, United States
Research Site

Bethesda, Maryland, 20817, United States
Research Site

Boston, Massachusetts, 02114, United States
Research Site

Detroit, Michigan, 48202, United States
Research Site

Rochester, Minnesota, 55905, United States
Research Site

St Louis, Missouri, 63110, United States
Research Site

Summit, New Jersey, 07901, United States
Research Site

Westbury, New York, 11590, United States
Research Site

Columbus, Ohio, 43210, United States
Research Site

Pittsburgh, Pennsylvania, 15212, United States
Research Site

Nashville, Tennessee, 37232, United States
Research Site

Austin, Texas, 78731, United States
Research Site

Dallas, Texas, 75246, United States
Research Site

Houston, Texas, 77030, United States
Research Site

Houston, Texas, 77090, United States
Research Site

Norfolk, Virginia, 23502, United States
Research Site

Seattle, Washington, 98104, United States
Research Site

Madison, Wisconsin, 53792-5666, United States
Research Site

Buenos Aires, C1125ABD, Argentina
Research Site

CABA, 1414, Argentina
Research Site

CABA, C1012AAR, Argentina
Research Site

CABA, C1019ABS, Argentina
Research Site

Ciudad de Buenos Aires, 1280, Argentina
Research Site

Córdoba, 5000, Argentina
Research Site

La Plata, 1900, Argentina
Research Site

Mar del Plata, 7600, Argentina
Research Site

Rosario, S2000DEJ, Argentina
Research Site

Rosario, S2002KDS, Argentina
Research Site

Adelaide, 5000, Australia
Research Site

Birtinya, 4575, Australia
Research Site

Darlinghurst, 2010, Australia
Research Site

Murdoch, 6150, Australia
Research Site

South Brisbane, 4101, Australia
Research Site

St Leonards, 2065, Australia
Research Site

Waratah, 2298, Australia
Research Site

Graz, 8036, Austria
Research Site

Innsbruck, 6020, Austria
Research Site

Anderlecht, 1070, Belgium
Research Site

Brussels, 1200, Belgium
Research Site

Charleroi, 6060, Belgium
Research Site

Edegem, 2650, Belgium
Research Site

Ghent, 9000, Belgium
Research Site

Leuven, 3000, Belgium
Research Site

Liège, 4000, Belgium
Research Site

Namur, 5000, Belgium
Research Site

Roeselare, 8800, Belgium
Research Site

Sint-Niklaas, 9100, Belgium
Research Site

Barretos, 14784-400, Brazil
Research Site

Belo Horizonte, 30110-022, Brazil
Research Site

Natal, 59075-740, Brazil
Research Site

Porto Alegre, 90610-000, Brazil
Research Site

Porto Alegre, 91350-200, Brazil
Research Site

Rio de Janeiro, 20560-120, Brazil
Research Site

São Paulo, 04038-034, Brazil
Research Site

São Paulo, 1323001, Brazil
Research Site

Sorocaba, 18030-510, Brazil
Research Site

Calgary, Alberta, T2N 5G2, Canada
Research Site

Edmonton, Alberta, T6G 1Z2, Canada
Research Site

Vancouver, British Columbia, V5Z 4E6, Canada
Research Site

Toronto, CA, M5G 2M9, Canada
Research Site

London, Ontario, N6A 5W9, Canada
Research Site

Toronto, Ontario, M4N 3M5, Canada
Research Site

Toronto, Ontario, M5G 1X5, Canada
Research Site

Montreal, Quebec, H3T 1E2, Canada
Research Site

Montreal, Quebec, H4A 3J1, Canada
Research Site

Sherbrooke, Quebec, J1H 5N4, Canada
Research Site

Baoding, 071000, China
Research Site

Beijing, 100006, China
Research Site

Beijing, 100044, China
Research Site

Changchun, 130021, China
Research Site

Changsha, 410008, China
Research Site

Changsha, 410013, China
Research Site

Dalian, 116001, China
Research Site

Foshan, 528000, China
Research Site

Fuzhou, 350011, China
Research Site

Guangzhou, 510060, China
Research Site

Guangzhou, 510080, China
Research Site

Guangzhou, 510120, China
Research Site

Hangzhou, 310003, China
Research Site

Hangzhou, 310020, China
Research Site

Hangzhou, 310022, China
Research Site

Harbin, 150081, China
Research Site

Hefei, 230001, China
Research Site

Jinan, 250001, China
Research Site

Linyi, 276000, China
Research Site

Nanchang, 330006, China
Research Site

Nanchang, 330009, China
Research Site

Nanjing, 210009, China
Research Site

Nanjing, 210029, China
Research Site

Nanning, 530021, China
Research Site

Shanghai, 200032, China
Research Site

Shenyang, 110015, China
Research Site

Tianjin, 300060, China
Research Site

Ürümqi, 830000, China
Research Site

Wuhan, 430079, China
Research Site

Xi'an, 710004, China
Research Site

Xi'an, 710061, China
Research Site

Zhengzhou, 450008, China
Research Site

Aalborg, 9000, Denmark
Research Site

Copenhagen Ø, 2100, Denmark
Research Site

Odense, 5000, Denmark
Research Site

Vejle, 7100, Denmark
Research Site

Avignon, 84918, France
Research Site

Besançon, 25000, France
Research Site

Bordeaux, 33000, France
Research Site

Brest, 29609, France
Research Site

Caen, 14076, France
Research Site

Dijon, 21079, France
Research Site

Le Mans, 72000, France
Research Site

Marseille, 13273, France
Research Site

Montpellier, 34298, France
Research Site

Nice, 06100, France
Research Site

Paris, 75005, France
Research Site

Pierre-Bénite, 69495, France
Research Site

Plerin SUR MER, 22190, France
Research Site

Rennes, 35000, France
Research Site

Saint-Cloud, 92210, France
Research Site

Saint-Herblain, 44805, France
Research Site

Tours, 37000, France
Research Site

Villejuif, 94805, France
Research Site

Berlin, 10117, Germany
Research Site

Dresden, 01307, Germany
Research Site

Freiburg im Breisgau, 79110, Germany
Research Site

Hanover, 30625, Germany
Research Site

München, 81675, Germany
Research Site

München, D-80336, Germany
Research Site

Münster, 48149, Germany
Research Site

Velbert, 42551, Germany
Research Site

Budapest, 1062, Hungary
Research Site

Budapest, 1122, Hungary
Research Site

Budapest, 1145, Hungary
Research Site

Győr, 9024, Hungary
Research Site

Kecskemét, 6000, Hungary
Research Site

Nyíregyháza, 4400, Hungary
Research Site

Szolnok, 5000, Hungary
Research Site

Tatabánya, 2800, Hungary
Research Site

Bengaluru, 560099, India
Research Site

Calicut, 673601, India
Research Site

Kolkata, 700160, India
Research Site

Marg Jaipur, 302004, India
Research Site

New Delhi, 110 085, India
Research Site

New Delhi, 110005, India
Research Site

New Delhi, 110017, India
Research Site

New Delhi, 110075, India
Research Site

Surat, 395002, India
Research Site

Thiruvananthapuram, 695011, India
Research Site

Haifa, 3109601, Israel
Research Site

Jerusalem, 9103102, Israel
Research Site

Jerusalem, 91120, Israel
Research Site

Kfar Saba, 44281, Israel
Research Site

Petah Tikva, 49100, Israel
Research Site

Ramat Gan, 52621, Israel
Research Site

Tel Aviv, 64239, Israel
Research Site

Aviano, 33081, Italy
Research Site

Bergamo, 24127, Italy
Research Site

Candiolo, 10060, Italy
Research Site

Cona, 44124, Italy
Research Site

Genova, 16132, Italy
Research Site

Livorno, 57124, Italy
Research Site

Messina, 98158, Italy
Research Site

Milan, 20141, Italy
Research Site

Milan, 20132, Italy
Research Site

Naples, 80131, Italy
Research Site

Padua, 35128, Italy
Research Site

Parma, Italy
Research Site

Prato, 59100, Italy
Research Site

Tricase, Lecce, 73039, Italy
Research Site

Udine, 33100, Italy
Research Site

Akashi-shi, 673-8558, Japan
Research Site

Bunkyō City, 113-8431, Japan
Research Site

Chiba, 260-8717, Japan
Research Site

Chūōku, 104-0045, Japan
Research Site

Fukuoka, 811-1395, Japan
Research Site

Gifu, 501-1194, Japan
Research Site

Hidaka-shi, 350-1298, Japan
Research Site

Hiroshima, 730-8518, Japan
Research Site

Isehara, 259-1193, Japan
Research Site

Kagoshima, 892-0833, Japan
Research Site

Kashiwa, 277-8577, Japan
Research Site

Kawasaki-shi, 216-8511, Japan
Research Site

Kitaadachi-gun, 362-0806, Japan
Research Site

Kōtoku, 135-8550, Japan
Research Site

Matsuyama, 791-0280, Japan
Research Site

Nagoya, 460-0001, Japan
Research Site

Naha, 901-0154, Japan
Research Site

Niigata, 951-8566, Japan
Research Site

Nishinomiya-shi, 663-8501, Japan
Research Site

Okayama, 700-8558, Japan
Research Site

Osaka, 541-8567, Japan
Research Site

Osakasayama-shi, 589-8511, Japan
Research Site

Sagamihara-shi, 252-0375, Japan
Research Site

Sapporo, 060-8648, Japan
Research Site

Shinagawa-ku, 142-8666, Japan
Research Site

Shinjuku-ku, 160-0023, Japan
Research Site

Shizuoka, 420-8527, Japan
Research Site

Tsu, 514-8507, Japan
Research Site

Yokohama, 241-8515, Japan
Research Site

Alc. Cuauhtémoc, 06700, Mexico
Research Site

Guadalajara Jalisco, 44280, Mexico
Research Site

Guadalajra, 44260, Mexico
Research Site

Mexico City, '14080, Mexico
Research Site

Mexico City, 0 3100, Mexico
Research Site

Mexico City, 6760, Mexico
Research Site

México, 04700, Mexico
Research Site

Monterrey, 64460, Mexico
Research Site

Nuevo León, 66278, Mexico
Research Site

Amsterdam, 1066 CX, Netherlands
Research Site

Breda, 4818 CK, Netherlands
Research Site

Hengelo, 7555 DL, Netherlands
Research Site

Leeuwarden, 8934 AD, Netherlands
Research Site

Rotterdam, 3015 GD, Netherlands
Research Site

Sittard-Geleen, 6162 BG, Netherlands
Research Site

Bydgoszcz, 85-796, Poland
Research Site

Koszalin, 75-581, Poland
Research Site

Krakow, 31-501, Poland
Research Site

Lodz, 90-302, Poland
Research Site

Rzeszów, 35-021, Poland
Research Site

Warsaw, 02-781, Poland
Research Site

Wroclaw, 53-413, Poland
Research Site

Lisbon, 1500-650, Portugal
Research Site

Lisbon, 1649-035, Portugal
Research Site

Lisbon, 1998-018, Portugal
Research Site

Krasnodar, 350040, Russia
Research Site

Moscow, 111123, Russia
Research Site

Moscow, 115478, Russia
Research Site

Moscow, 117997, Russia
Research Site

Moscow, 121205, Russia
Research Site

Saint Petersburg, 190103, Russia
Research Site

Saint Petersburg, 195271, Russia
Research Site

Saint Petersburg, 197758, Russia
Research Site

Yaroslavl, 150054, Russia
Research Site

Dammam, 31444, Saudi Arabia
Research Site

Jeddah, 21423, Saudi Arabia
Research Site

Jeddah, 23214, Saudi Arabia
Research Site

Riyadh, 11426, Saudi Arabia
Research Site

Riyadh, 11525, Saudi Arabia
Research Site

Riyadh, 12713, Saudi Arabia
Research Site

Bukit Merah, 169610, Singapore
Research Site

Singapore, 119074, Singapore
Research Site

Singapore, 258499, Singapore
Research Site

Singapore, 308433, Singapore
Research Site

Singapore, 329563, Singapore
Research Site

Daegu, 41404, South Korea
Research Site

Goyang-si, 10408, South Korea
Research Site

Incheon, 22332, South Korea
Research Site

Seongnam-si, 13620, South Korea
Research Site

Seoul, 02841, South Korea
Research Site

Seoul, 03080, South Korea
Research Site

Seoul, 03722, South Korea
Research Site

Seoul, 05505, South Korea
Research Site

Seoul, 06351, South Korea
Research Site

A Coruña, 15006, Spain
Research Site

Barcelona, 08035, Spain
Research Site

Barcelona, 08036, Spain
Research Site

Barcelona, 08907, Spain
Research Site

Córdoba, 14004, Spain
Research Site

El Palmar, 30120, Spain
Research Site

Madrid, 28005, Spain
Research Site

Madrid, 28007, Spain
Research Site

Madrid, 28046, Spain
Research Site

San Sebastián, 20014, Spain
Research Site

Seville, 41013, Spain
Research Site

Valencia, 46026, Spain
Research Site

Gothenburg, 413 45, Sweden
Research Site

Örebro, 701 85, Sweden
Research Site

Stockholm, 118 83, Sweden
Research Site

Uppsala, 751 85, Sweden
Research Site

Vaxjo, 35185, Sweden
Research Site

Taichung, 40447, Taiwan
Research Site

Tainan, 70403, Taiwan
Research Site

Tainan, 710, Taiwan
Research Site

Taipei, 10048, Taiwan
Research Site

Taipei, 10449, Taiwan
Research Site

Taipei, 11217, Taiwan
Research Site

Taipei, 235, Taiwan
Research Site

Taoyuan District, 333, Taiwan
Research Site

Cambridge, CB2 0QQ, United Kingdom
Research Site

Cardiff, CF14 2TL, United Kingdom
Research Site

Edinburgh, EH4 2XR, United Kingdom
Research Site

Guildford, United Kingdom
Research Site

Leeds, LS9 7TF, United Kingdom
Research Site

London, SE1 9RT, United Kingdom
Research Site

Manchester, M20 4BX, United Kingdom
Research Site

Northwood, HA6 2RN, United Kingdom

Conditions

Explore the condition pages connected to this study.

ADVANCED OR METASTATIC BREAST CANCER