Suicide-Gene t cells aim to stop blood cancer relapse
NCT ID NCT04180059
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether infusing specially designed immune cells can prevent blood cancer from coming back after a stem cell transplant. The cells target a specific protein (HLA-DPB1*04:01) found on many cancer cells and include a 'suicide switch' to turn them off if needed. Six adults with certain blood cancers who have already received a transplant from a donor without that protein will receive increasing doses of these cells. The main goal is to find a safe dose that does not cause severe graft-versus-host disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Chu de Nantes
RECRUITINGNantes, France
Contact Email: •••••@•••••