New drug duo targets Hard-to-Treat breast cancer

NCT ID NCT07597629

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two drugs together for people with advanced breast cancer that cannot be removed by surgery. SYS6023 targets a protein called HER3 on cancer cells, while KN026 targets HER2. The goal is to see if the combination is safe and shrinks tumors. About 36 adults with confirmed HER3-positive breast cancer will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SYS6023 (a drug that targets HER3 on cancer cells) and KN026 (a drug that targets HER2 on cancer cells)

What this could lead to

If successful, this combination could offer a new treatment option for people with advanced breast cancer that has not responded to other therapies.

What could go wrong

This is an early Phase II trial with only 36 participants, so results may not apply to everyone. The drugs may cause side effects or fail to shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Tumor Hospital of Harbin

    RECRUITING

    Harbin, Heilonjiang, 150000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••