Could adding a common antibiotic boost syphilis cure rates in HIV patients?

NCT ID NCT06069141

First seen Nov 18, 2025 · Last updated May 14, 2026 · Updated 22 times

Summary

This study tests whether adding doxycycline to the standard penicillin shot works better for treating early syphilis in people with HIV. About 688 adults will be randomly assigned to get either penicillin alone or penicillin plus a 7-day course of doxycycline pills. The main goal is to see if the combination leads to a better drop in syphilis blood test levels at 24 and 48 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chi Mei Medical Hospital

    RECRUITING

    Tainan, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Far Eastern Memorial Hospital

    RECRUITING

    Taipei, Taiwan, 110, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kaohsiung Veterans General Hospital

    RECRUITING

    Kaohsiung City, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cheng-Kung University Hospital

    RECRUITING

    Tainan, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taiwan, 110, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Taiwan University Hospital Hsin-Chu Branch

    RECRUITING

    Hsinchu, Taiwan, 110, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taipei Vetetrans General Hospital

    RECRUITING

    Taipei, Taiwan, 110, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Taoyuan General Hospital

    RECRUITING

    Taoyuan, Taiwan, 110, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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