A new kind of MRI aims to watch brain connections change in seconds

NCT ID NCT01686516

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study tests whether a type of diffusion MRI can detect rapid, activity-driven changes in brain connections — called synaptic plasticity — during visual stimulation. Researchers will scan healthy adults aged 20–30 and 60–80 to compare how the aging brain responds. If successful, the method could offer a new way to study brain health without using radioactive tracers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If diffusion MRI can reliably track synaptic plasticity, it could become a new tool for studying brain aging and early signs of decline.
What could go wrong
This is a small, early-stage methodological study in healthy volunteers. The technique may not prove sensitive or specific enough for clinical use.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Inserm U 825

    Toulouse, France, 31059, France

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