New device could help patients with Hard-to-Control blood pressure
NCT ID NCT07081243
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study follows 500 people in China with resistant hypertension who have already received the Symplicity Spyral renal denervation system. The device uses radiofrequency energy to calm overactive kidney nerves that can raise blood pressure. Researchers will track blood pressure changes, medication use, and safety for up to 36 months to see if the treatment provides lasting benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Symplicity Spyral Renal Denervation System (a device that uses radiofrequency energy to disrupt nerves in the kidney arteries to lower blood pressure)
- What this could lead to
- If successful, this could confirm that renal denervation provides lasting blood pressure reduction for people with resistant hypertension, offering an alternative to lifelong medication.
- What could go wrong
- This is an observational study, not a randomized trial, so results may be less definitive. The device is already approved, but long-term durability and safety in a real-world Chinese population are still being assessed.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RESISTANT HYPERTENSION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Zhongshan Hospital Fudan University
RECRUITINGShanghai, Shanghai Municipality, 210000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a simple heart-rate test reveal who is truly taking their blood pressure pills?
- New hope for stubborn high blood pressure? phase 3 trial launches
- Talking to a nurse may ease blood pressure pill side effects
- New study seeks to identify who benefits from Last-Resort blood pressure drugs
- Skin blood flow test may predict heart danger in tough-to-treat high blood pressure
- Beetroot breakthrough? new study tests natural BP fix for tough hypertension