New cream shows promise for rare, severe skin condition

NCT ID NCT05211830

First seen Jan 05, 2026 · Last updated May 17, 2026 · Updated 18 times

Summary

This study tested a cream called SXR1096 in 9 people with Netherton syndrome, a rare genetic skin disease that causes redness, scaling, and itching. The cream aims to block certain enzymes that drive the disease. Participants applied the cream to some skin areas and a placebo to others for one month to compare safety and effectiveness.

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Contacts and locations

Locations

  • Karolinska Hospital, Huddinge

    Stockholm, Sweden

  • Medical University Innsbruck, Tirol Kliniken

    Innsbruck, Austria

  • Necker Hospital

    Paris, France

  • Saint Louis Hospital

    Paris, 75010, France

  • University of Freiburg

    Freiburg im Breisgau, Germany

Conditions

Explore the condition pages connected to this study.