New cream shows promise for rare skin condition

NCT ID NCT05211830

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tested a cream called SXR1096 on 9 people with Netherton syndrome, a rare inflammatory skin disease. The cream aims to block certain enzymes that cause skin problems. Participants applied the cream and a placebo to different skin areas for one month to check safety and effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SXR1096 cream

What this could lead to

If it works, this could point toward a treatment that controls the severe skin inflammation in Netherton syndrome.

What could go wrong

This is a very early, small trial with only 9 people. The cream may not work better than placebo, and side effects are unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Netherton syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Karolinska Hospital, Huddinge

    Stockholm, Sweden

  • Medical University Innsbruck, Tirol Kliniken

    Innsbruck, Austria

  • Necker Hospital

    Paris, France

  • Saint Louis Hospital

    Paris, 75010, France

  • University of Freiburg

    Freiburg im Breisgau, Germany