New drug trial aims to unleash immune system against skin cancer

NCT ID NCT03161431

Summary

This early-stage study is testing a new oral drug called SX-682 in people with advanced melanoma that has spread. The goal is to see if SX-682 can safely block certain cells that shield the tumor, allowing the patient's own immune system, boosted by an existing immunotherapy drug, to better attack the cancer. Participants will take SX-682 alone for 21 days, then in combination with pembrolizumab for up to two years.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • MD Anderson

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital Cancer Center

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • University of Miami

    Miami, Florida, 33136, United States

  • Wilmot Cancer Institute - University of Rochester

    Rochester, New York, 14642, United States

Conditions

Explore the condition pages connected to this study.