Could a treatment switch cut infection risk in MS patients?

NCT ID NCT06854094

First seen Mar 12, 2026 · Last updated May 15, 2026 · Updated 12 times

Summary

This study looks at whether switching from anti-CD20 drugs (like ocrelizumab) to cladribine can improve immune function and lower infection risk in people with relapsing multiple sclerosis. About 70 participants will be followed for 2 years. The goal is to see if the switch helps stabilize antibody levels and reduce infections compared to staying on anti-CD20 therapy.

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Contacts and locations

Locations

  • Ospedale Regionale di Lugano, Istituto di Neuroscienze Cliniche della Svizzera Italiana, Via Tesserete 46,

    Lugano, Canton Ticino, 6903, Switzerland

Conditions

Explore the condition pages connected to this study.