New pill shows promise for rare gut tumors

NCT ID NCT05077384

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a daily pill called surufatinib in 36 Japanese patients with neuroendocrine tumors that had stopped responding to other treatments. The goal was to see if the drug is safe and whether it can shrink tumors. The trial combined an early safety phase with a later phase measuring tumor response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surufatinib (a drug taken by mouth once daily)

What this could lead to

If successful, surufatinib could offer a new treatment option for patients with neuroendocrine tumors that have stopped responding to standard therapies.

What could go wrong

This is an early-phase study with only 36 participants, so results may not apply broadly. Side effects are possible, and the drug may not shrink tumors in all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aichi Cancer Centre

    Nagoya, 464-8681, Japan

  • Fukuoka Sanno Hospital

    Fukuoka, 814-0001, Japan

  • Hokkaido University Hospital

    Sapporo, 060-8648, Japan

  • Kagawa University Hospital

    Kagawa, 761-0793, Japan

  • Kansia Electric Power Hospital

    Osaka, 553-0003, Japan

  • Kyorin University Hospital

    Mitaka, 181-8611, Japan

  • Kyoto University Hospital

    Kyoto, 606-8507, Japan

  • Kyushu University Hospital

    Fukuoka, 812-0054, Japan

  • National Cancer Centre Hospital

    Tokyo, 104-004, Japan

  • National Cancer Centre Hospital East

    Kashiwa-shi, 277-8577, Japan

  • Tohoku University Hospital

    Sendai, 890-8574,, Japan

  • Yokohama City University Hospital

    Yokohama, 236-0004, Japan