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New study tests less drastic surgery to prevent ovarian cancer

NCT ID NCT02760849

Ongoing Prevention Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

Summary

This study is comparing two different surgeries to prevent ovarian cancer in premenopausal women who have inherited genetic mutations that put them at high risk. One surgery removes both the fallopian tubes and ovaries at once, while the other removes just the tubes first and delays removing the ovaries. Researchers want to see which approach better lowers cancer risk while also improving sexual function and overall well-being for these women.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Siteman Cancer Center at Washington University

    St Louis, Missouri, 63110, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.

DELETERIOUS BARD1 GENE MUTATION DELETERIOUS BRCA1 GENE MUTATION DELETERIOUS BRCA2 GENE MUTATION DELETERIOUS BRIP1 GENE MUTATION DELETERIOUS EPCAM GENE MUTATION DELETERIOUS MLH1 GENE MUTATION DELETERIOUS MSH2 GENE MUTATION DELETERIOUS MSH6 GENE MUTATION DELETERIOUS PALB2 GENE MUTATION DELETERIOUS PMS2 GENE MUTATION DELETERIOUS RAD51C GENE MUTATION DELETERIOUS RAD51D GENE MUTATION HEREDITARY BREAST AND OVARIAN CANCER SYNDROME PREMENOPAUSAL