Can a common spice boost liver health in fatty liver disease?
NCT ID NCT07768657
First seen Aug 17, 2026 · Last updated Aug 17, 2026
Summary
This trial tests whether adding sumac spice to a calorie-restricted diet can improve liver function and metabolic health in adults with obesity and non-alcoholic fatty liver disease (NAFLD). About 100 participants aged 30-60 will be randomly assigned to take either a placebo or one of two doses of sumac daily for 12 weeks. Researchers will measure changes in liver enzymes, blood sugar, insulin resistance, cholesterol, and inflammation to see if sumac offers extra benefits beyond diet alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sumac (Rhus coriaria L.) supplement at 1.5 g/day or 3.0 g/day, combined with a calorie-restricted diet (1250-1300 kcal/day) for 12 weeks.
- What this could lead to
- If sumac proves effective, it could offer a natural, low-cost addition to diet plans for improving liver function and metabolic health in people with fatty liver disease.
- What could go wrong
- This is a small, early-stage trial, and results may not be conclusive. The benefits of sumac beyond calorie restriction alone are uncertain, and individual responses may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sana Noreen
Lahore, Punjab Province, 54000, Pakistan
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