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Two cheap creams go head to head against scabies mites

NCT ID NCT07822672

Cure Sponsor: Can Tho University of Medicine and Pharmacy Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Scabies is a skin condition caused by mites that burrow into the skin and cause intense itching. This trial compares two creams used to treat it: sulfur 7% and permethrin 5%. Ninety adults with scabies were assigned to one cream or the other. Sulfur was applied each evening for three nights; permethrin was applied once overnight and repeated after a week. Researchers checked whether the scabies cleared at two and four weeks, and also tracked itching, sleep, side effects, satisfaction, and cost.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sulfur 7% cream compared with permethrin 5% cream
What this could lead to
If sulfur cream works as well as permethrin, doctors and patients could have a second low-cost option for clearing scabies, which may help when permethrin is unavailable or unaffordable.
What could go wrong
The trial is small, with 90 adults, and it is open-label, so participants and researchers know which cream was used. That can bias how people report itching, sleep, and satisfaction. Sulfur can irritate skin and has a strong odor, which may affect how well people tolerate it.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

90 people

The number who actually took part.

Started

Jun 2024

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Clinical diagnosis of ordinary (non-crusted) scabies, established using the 2020 International Alliance for the Control of Scabies (IACS) consensus criteria, category B: * B1: burrow identified, or * B2: typical lesions at male genitalia, or * B3: typical lesions at typical sites plus pruritus and a history of close contact with a person with scabies or itch Exclusion Criteria: * Known allergy or intolerance to sulfur or permethrin * Pregnant or breastfeeding women * Hearing, visual, or cognitive impairment preventing reliable self-reporting of symptoms * Self-discontinuation of study treatment before completion

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Conditions

The condition(s) this trial relates to.

Pruritus scabies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Scabies

Contacts and locations

Locations

  • Can Tho Dermatology Hospital

    Can Tho, Can Tho City, 900000, Vietnam

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