Broccoli compound may shield hearts from chemo damage

NCT ID NCT03934905

Recruiting now Disease control Sponsor: Texas Tech University Health Sciences Center Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This trial investigates whether sulforaphane, a nutrient found in broccoli, can reduce heart damage caused by the chemotherapy drug doxorubicin in breast cancer patients. About 70 participants will receive either sulforaphane or a placebo alongside their chemotherapy. The study measures changes in heart function and signs of heart injury to see if the supplement offers protection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sulforaphane (a nutrient found in broccoli and other cruciferous vegetables)
What this could lead to: If it works, this could lead to a simple dietary supplement that helps prevent heart damage from a common chemotherapy drug, improving safety for breast cancer patients.
What could go wrong: This is an early-phase trial with only 70 participants, so results may not apply to everyone. The supplement may not protect the heart or could interact with chemotherapy in unexpected ways.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer cardiomyopathy due to anthracyclines Cardiotoxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTHRACYCLINE RELATED CARDIOTOXICITY IN BREAST CANCER

Contacts and locations

Locations

Texas Tech University Health Sciences Center
RECRUITING

Lubbock, Texas, 79430, United States

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