New drug may get your gut moving faster after hernia repair

NCT ID NCT05985343

Completed Symptom relief Sponsor: Clayton Petro Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether sugammadex, a drug used to reverse muscle relaxants after surgery, could help patients regain bowel function faster than standard care. 184 adults undergoing open abdominal wall reconstruction for ventral hernia were randomly assigned to receive either sugammadex or the usual reversal drugs. The main goal was to see how quickly patients could eat solid food and have their first bowel movement after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sugammadex
What this could lead to: If it works, sugammadex could help patients recover bowel function faster after abdominal wall surgery, reducing hospital stays.
What could go wrong: This is a small, completed Phase 4 trial with 184 patients, so results may not apply to everyone. Sugammadex can cause allergic reactions in some people.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hernia, Ventral ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HERNIA, VENTRAL ILEUS

Contacts and locations

Locations

Cleveland Clinic Center for Abdominal Core Health

Cleveland, Ohio, 44195, United States

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