New drug may get your gut moving faster after hernia repair

NCT ID NCT05985343

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether sugammadex, a drug used to reverse muscle relaxants after surgery, could help patients regain bowel function faster than standard care. 184 adults undergoing open abdominal wall reconstruction for ventral hernia were randomly assigned to receive either sugammadex or the usual reversal drugs. The main goal was to see how quickly patients could eat solid food and have their first bowel movement after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sugammadex

What this could lead to

If it works, sugammadex could help patients recover bowel function faster after abdominal wall surgery, reducing hospital stays.

What could go wrong

This is a small, completed Phase 4 trial with 184 patients, so results may not apply to everyone. Sugammadex can cause allergic reactions in some people.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hernia, Ventral ileus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic Center for Abdominal Core Health

    Cleveland, Ohio, 44195, United States