Anesthesia reversal drug may trigger jaw spasms – study investigates risks

NCT ID NCT06962007

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study looks at whether sugammadex, a drug used to reverse muscle relaxants after surgery, causes jaw clenching. Researchers will compare different doses of sugammadex to a standard reversal combination in adults undergoing elective surgery. The goal is to understand how often clenching occurs, how severe it is, and what factors increase the risk, such as dose or patient characteristics. Findings could help anesthesiologists adjust treatment to improve safety during recovery from anesthesia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sugammadex
What this could lead to
If successful, this study could help anesthesiologists choose safer doses or alternative drugs to prevent jaw clenching during surgery recovery.
What could go wrong
This is an early-stage observational study, not a treatment trial. It may not identify clear risk factors, and results may not apply to all surgical patients.

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Conditions

The condition(s) this trial relates to.

Trismus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wonkwang University hospital

    RECRUITING

    Iksan, Jeonbuk-do, 54538, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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