Milk under the tongue: a new hope for kids with dairy allergy?
NCT ID NCT00874627
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether giving small amounts of milk under the tongue (sublingual immunotherapy) could help children with cow milk allergy tolerate more milk. Fifty-one children aged 5 and older with confirmed IgE-mediated cow milk allergy participated. Over 12 months, researchers measured how much milk the children could safely drink before reacting, along with skin reactions and allergy blood tests.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- milk
- What this could lead to
- If it works, this could offer a way to help children with cow milk allergy safely consume more milk without severe reactions.
- What could go wrong
- This is a small, early-phase study with only 51 children, so results may not apply to everyone. There is also a risk of allergic reactions during treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Hospital Cochin - Saint-Vincent de Paul
Paris, 75679, France
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Other studies related to the condition(s) this trial covers.