Tiny corneal pockets tested as Suture-Free seal for cataract incisions
NCT ID NCT07821203
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers at the Philippine Eye Research Institute studied a surgical technique called a sub-incisional pocket (SIP) for sealing the small corneal incisions made during cataract surgery. The study reviewed records from 35 adults who had routine phacoemulsification with a clear corneal incision. The team graded how well the wounds sealed on the first day after surgery and tracked changes in astigmatism over time. The goal is to see whether this pocket technique offers a safe and effective way to close corneal wounds without stitches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sub-incisional pocket (SIP), a surgical wound-sealing technique using two non-penetrating corneal incisions placed before the main cataract incision
- What this could lead to
- If the technique seals incisions reliably, it could offer cataract surgeons a simple way to close corneal wounds without sutures and possibly reduce post-surgery astigmatism.
- What could go wrong
- This is a small retrospective study of 35 eyes, so it cannot prove the technique works better than standard care. Results may not apply to other surgeons, and the study cannot rule out complications that appear later.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
-
35 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients that have undergone phacoemulsification with the sub-incisional pocket (SIP) from the Peregrine Eye and Laser Institute within the set study period of January 1, 2025 to February 28, 2026.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult (≥18 years) participants * Patients undergoing primary phacoemulsification with clear corneal incision and in-the-bag intraocular acrylic lens * Uncomplicated cataract surgeries utilizing a 2.2 mm temporal clear corneal incision with sub-incisional stromal pocket. Exclusion Criteria: * Medical records from patients with intraoperative complications requiring incisions or suturing * Prior surgery in the operative eye * Prior corneal disease or ocular surface disease * With an inadequate follow-up within 7 days after surgery
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Peregrine Eye and Laser Institute
Makati City, Philippines
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Other studies related to the condition(s) this trial covers.
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