Selective t cell removal may reduce transplant complications in leukemia patients
NCT ID NCT02220985
First seen Jun 08, 2026 · Last updated Jun 08, 2026
Summary
This study tested a method to prevent graft-versus-host disease (GVHD) in 84 leukemia patients receiving donor stem cell transplants. By removing a specific type of immune cell (naive T cells) from the donor graft, researchers aimed to lower GVHD risk while preserving infection-fighting and anti-leukemia effects. The approach was evaluated in patients with various leukemias and myelodysplastic syndrome, using related or unrelated donors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
Conditions
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Conditions inferred from the trial description
These were inferred from the trial's summary, not listed by the trial registrant.